The best Kodi skin for you depends on what's important. There are a number of factors to consider.
Are you using a touch based device?
If so, you will need touch support.
Do you need live TV/PVR functionality?
Make sure you select a skin that supports live TV/PVR
These are just a few of the options available. To find the best skin for you, go to the front page of the site and select the filters on the left that are important to you.
The skins are then sorted by rating, so you can find the top rated skins with the features you need.